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S. B. Kribbs, F. J. Clubb, L. H. Michael, V. V. Didenko, P. J. Hornsby, Y. Seta, H. Oral, F. G. Spinale, and D. L. Mann. Pathophysiologically relevant concentrations of tumor necrosis factor-a promote progressive left ventricular dysfunction and remodeling in rats. Circulution 97: 1382-1391, 1998. Bradley, J. , D. R. Johnson, and J. S. Pober. Four different classes of inhibitors of receptormediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells. J Immunol 150: 5544-5555, 1993.

Eur J Immunol25: 2183-2189, 1995. , D. Ferrari, M. Los, S. Wesselborg, and M. E. Peter. Apoptosis signaling by death receptors. Eur J Biochem 254: 439-459, 1998. , H. Morawietz, K. Hakim, H. R. Zerkowski, T. Eschenhagen, J. Holtz, and D. Darmer. Alternative splicing of the primary Fas transcript generating soluble Fas antagonists is suppressed in the failing human ventricular myocardium. Biochem Biophys Res Comm 239: 794798, 1997. Screaton, G. , J. Monkolsapaya, X. N. Xu, A. E. Cowper, A. J. McMichael, and J.

Goeddel. Prevention of constitutive TNF receptor signaling by silencer of death domains. Science 283: 543-546, 1999. Kagan, B. , R. L. Baldwin, D. Munoz, and B. J. Wisnieski. Formation of ion-permeable channels by tumor necrosis factor-a. Science 257: 1427-1430, 1993. , K. Kito, H. P. Nguyen, H. -K. , and E. T. Yeh. Identification of three sentrinization sites in PML. JBiol Chew 273: 26675-26682, 1998. , H. P. Nguyen, and E. T. Yeh. Preferential modification of nuclear proteins by a novel ubiquitin-like molecule.

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